![]() ![]() This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. ![]() ![]() This cytokine is mainly secreted by macrophages. Database of Single Nucleotide Polymorphisms (dbSNP)įull Name tumor necrosis factor provided by HGNC Primary source HGNC:HGNC:11892 See related Ensembl:ENSG00000232810 MIM:191160 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo Also known as DIF TNFA TNFSF2 TNLG1F TNF-alpha Summary This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily.Database of Genomic Structural Variation (dbVar).Online Mendelian Inheritance in Man (OMIM).Database of Genotypes and Phenotypes (dbGaP).Structure (Molecular Modeling Database).Conserved Domain Search Service (CD Search).BLAST (Basic Local Alignment Search Tool). ![]()
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